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Page 1
Did you mean mep and neoplasms (588 results)?
Exome sequencing and characterization of 49,960 individuals in the UK Biobank.
Van Hout CV, Tachmazidou I, Backman JD, Hoffman JD, Liu D, Pandey AK, Gonzaga-Jauregui C, Khalid S, Ye B, Banerjee N, Li AH, O'Dushlaine C, Marcketta A, Staples J, Schurmann C, Hawes A, Maxwell E, Barnard L, Lopez A, Penn J, Habegger L, Blumenfeld AL, Bai X, O'Keeffe S, Yadav A, Praveen K, Jones M, Salerno WJ, Chung WK, Surakka I, Willer CJ, Hveem K, Leader JB, Carey DJ, Ledbetter DH; Geisinger-Regeneron DiscovEHR Collaboration; Cardon L, Yancopoulos GD, Economides A, Coppola G, Shuldiner AR, Balasubramanian S, Cantor M; Regeneron Genetics Center; Nelson MR, Whittaker J, Reid JG, Marchini J, Overton JD, Scott RA, Abecasis GR, Yerges-Armstrong L, Baras A. Van Hout CV, et al. Nature. 2020 Oct;586(7831):749-756. doi: 10.1038/s41586-020-2853-0. Epub 2020 Oct 21. Nature. 2020. PMID: 33087929 Free PMC article.
In addition to replicating established associations, we found novel LOF variants with large effects on disease traits, including PIEZO1 on varicose veins, COL6A1 on corneal resistance, MEPE on bone density, and IQGAP2 and GMPR on blood cell traits. We further demonstrate t …
In addition to replicating established associations, we found novel LOF variants with large effects on disease traits, including PIEZO1 on v …
The wrickkened pathways of FGF23, MEPE and PHEX.
Rowe PS. Rowe PS. Crit Rev Oral Biol Med. 2004 Sep 1;15(5):264-81. doi: 10.1177/154411130401500503. Crit Rev Oral Biol Med. 2004. PMID: 15470265 Free PMC article. Review.
In OHO, over-expression of FGF23 and/or MEPE is proposed to result in abnormal renal-phosphate handling and mineralization. ...The following review will present a global hypothesis that attempts to explain the experimental and clinical observations in HYP, ADHR, and OHO, p …
In OHO, over-expression of FGF23 and/or MEPE is proposed to result in abnormal renal-phosphate handling and mineralization. ...The fo …
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia.
Rowe PS, de Zoysa PA, Dong R, Wang HR, White KE, Econs MJ, Oudet CL. Rowe PS, et al. Genomics. 2000 Jul 1;67(1):54-68. doi: 10.1006/geno.2000.6235. Genomics. 2000. PMID: 10945470
MEPE is 525 residues in length with a short N-terminal signal peptide. High-level expression of MEPE mRNA occurred in all four OHO tumors screened. Three of 11 non-OHO tumors screened contained trace levels of MEPE expression (detected only after RT-PCR and S …
MEPE is 525 residues in length with a short N-terminal signal peptide. High-level expression of MEPE mRNA occurred in all four …
Expression of the SIBLINGs and their MMP partners in human benign and malignant prostate neoplasms.
Anunobi CC, Koli K, Saxena G, Banjo AA, Ogbureke KU. Anunobi CC, et al. Oncotarget. 2016 Jul 26;7(30):48038-48049. doi: 10.18632/oncotarget.10110. Oncotarget. 2016. PMID: 27331624 Free PMC article.
The other two family members are dentin sialophosphoprotein (DSPP) and matrix extracellular phosphoglycoprotein (MEPE). The specific SIBLING-MMP pairing reported in some cancers have not been reported in prostate neoplasms. ...MEPE was significantly upregulat …
The other two family members are dentin sialophosphoprotein (DSPP) and matrix extracellular phosphoglycoprotein (MEPE). The specific …
Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank.
Sandoval-Plata G, Morgan K, Abhishek A. Sandoval-Plata G, et al. Ann Rheum Dis. 2021 Sep;80(9):1220-1226. doi: 10.1136/annrheumdis-2020-219796. Epub 2021 Apr 8. Ann Rheum Dis. 2021. PMID: 33832965
RESULTS: Thirteen independent single nucleotide polymorphisms (SNPs) in ABCG2, SLC2A9, SLC22A11, GCKR, MEPE, PPM1K-DT, LOC105377323 and ADH1B reached genome-wide significance and replicated as predictors of AH to gout transition. ...
RESULTS: Thirteen independent single nucleotide polymorphisms (SNPs) in ABCG2, SLC2A9, SLC22A11, GCKR, MEPE, PPM1K-DT, LOC105377323 a …
mEPE-score: a comprehensive grading system for predicting pathologic extraprostatic extension of prostate cancer at multiparametric magnetic resonance imaging.
Gatti M, Faletti R, Gentile F, Soncin E, Calleris G, Fornari A, Oderda M, Serafini A, Strazzarino GA, Vissio E, Bergamasco L, Cirillo S, Papotti MG, Gontero P, Fonio P. Gatti M, et al. Eur Radiol. 2022 Jul;32(7):4942-4953. doi: 10.1007/s00330-022-08595-9. Epub 2022 Mar 15. Eur Radiol. 2022. PMID: 35290508 Free PMC article.
The performance of mEPE features was evaluated using the five diagnostic parameters and ROC curve analysis. ...CONCLUSIONS: The individual mEPE features have low sensitivity and high specificity. The use of mEPE-score allows for consistent and reliable assess …
The performance of mEPE features was evaluated using the five diagnostic parameters and ROC curve analysis. ...CONCLUSIONS: The indiv …
Matrix extracellular phosphoglycoprotein is expressed in causative tumors of oncogenic osteomalacia.
Imanishi Y, Hashimoto J, Ando W, Kobayashi K, Ueda T, Nagata Y, Miyauchi A, Koyano HM, Kaji H, Saito T, Oba K, Komatsu Y, Morioka T, Mori K, Miki T, Inaba M. Imanishi Y, et al. J Bone Miner Metab. 2012 Jan;30(1):93-9. doi: 10.1007/s00774-011-0290-8. Epub 2011 Jul 8. J Bone Miner Metab. 2012. PMID: 21739089
Although the presence of MEPE mRNA has been reported in some OOM tumors, little is known about the prevalence of MEPE expression in OOM tumors. ...These results indicate that, in addition to the hypophosphatemic effects of FGF-23, MEPE or the MEPE-deri …
Although the presence of MEPE mRNA has been reported in some OOM tumors, little is known about the prevalence of MEPE expressi …
[SIBLING proteins: molecular tools for tumor progression and angiogenesis].
Lamour V, Nokin MJ, Henry A, Castronovo V, Bellahcène A. Lamour V, et al. Med Sci (Paris). 2013 Nov;29(11):1018-25. doi: 10.1051/medsci/20132911019. Epub 2013 Nov 20. Med Sci (Paris). 2013. PMID: 24280506 Free article. Review. French.
The small integrin-binding ligand N-linked glycoprotein (SIBLING) family consists of osteopontin (OPN), bonesialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP) and matrix extracellular phosphoglycoprotein (MEPE). These proteins, initially …
The small integrin-binding ligand N-linked glycoprotein (SIBLING) family consists of osteopontin (OPN), bonesialoprotein (BSP), dentin matri …
26 results